Shopping Cart

Remove All

Your shopping cart is currently empty

ML-098

Select Batch

Purity:99.52%

Resource Download

COA HNMR HPLC

ML-098

Catalog No. T4619Cas No. 878978-76-8

ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$33	In Stock
2 mg	$45	In Stock
5 mg	$64	In Stock
10 mg	$100	In Stock
25 mg	$211	In Stock
50 mg	$297	In Stock
100 mg	$415	In Stock
500 mg	$983	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "ML-098"

Product Introduction

Bioactivity

Description	ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
In vitro	ML098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)[1].
Alias	CID-7345532

Chemical Properties

Molecular Weight	309.36
Formula	C19H19NO3
Cas No.	878978-76-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (161.6 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2325 mL	16.1624 mL	32.3248 mL	161.6240 mL
5 mM	0.6465 mL	3.2325 mL	6.4650 mL	32.3248 mL
10 mM	0.3232 mL	1.6162 mL	3.2325 mL	16.1624 mL
20 mM	0.1616 mL	0.8081 mL	1.6162 mL	8.0812 mL
50 mM	0.0646 mL	0.3232 mL	0.6465 mL	3.2325 mL
100 mM	0.0323 mL	0.1616 mL	0.3232 mL	1.6162 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc