Shopping Cart

Remove All

Your shopping cart is currently empty

Monensin sodium salt

Select Batch

Purity:98.9%

Resource Download

COA HNMR HPLC

Monensin sodium salt

Catalog No. T1033Cas No. 22373-78-0

Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
50 mg	$30	In Stock
100 mg	$42	In Stock
200 mg	$58	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Monensin sodium salt"

Product Introduction

Bioactivity

Description	Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion
In vitro	Monensin sodium salt (Coban), isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics. Monensin is an ionophore related to the crown ethers with a preference to form complexes with monovalent cations such as: Li+, Na+, K+, Rb+, Ag+, and TI+. [1] Monensin A is able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport, and exhibits antibiotic, antimalarial, and other biological activities. [2] The antibacterial properties of monensin and its derivatives are a result of their ability to transport metal cations through cellular and subcellular membranes. [3]
In vivo	LD50: Mice 335 mg/kg (i.g.) [4]; Rats 36.5 mg/kg (i.g.); Chickens 185 mg/kg (i.g.). [5]
Alias	Sodium Monensin, Monensin A sodium salt

Chemical Properties

Molecular Weight	692.85
Formula	C36H61NaO11
Cas No.	22373-78-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: < 1mg/ml (insoluble）

Ethanol: 69.3 mg/mL (100 mM)

Solution Preparation Table

Ethanol

	1mg	5mg	10mg	50mg
1 mM	1.4433 mL	7.2166 mL	14.4331 mL	72.1657 mL
5 mM	0.2887 mL	1.4433 mL	2.8866 mL	14.4331 mL
10 mM	0.1443 mL	0.7217 mL	1.4433 mL	7.2166 mL
20 mM	0.0722 mL	0.3608 mL	0.7217 mL	3.6083 mL
50 mM	0.0289 mL	0.1443 mL	0.2887 mL	1.4433 mL
100 mM	0.0144 mL	0.0722 mL	0.1443 mL	0.7217 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc