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NCC007

NCC007
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Purity:98.11%
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NCC007

Catalog No. T7949Cas No. 2342583-66-6
NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$98In Stock
25 mg$179In Stock
50 mg$297In Stock
100 mg$438In Stock
500 mg$982In Stock
1 mL x 10 mM (in DMSO)$71In Stock
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Product Introduction

Bioactivity
Description
NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.
In vitro
In vitro kinase assay showed that NCC007 inhibited CKIα and CKIδ with an IC50 of 1.8 and 3.6 μM.
In vivo
NCC007 lengthened the period of mouse behavioral rhythms in vivo.
Chemical Properties
Molecular Weight447.5
FormulaC22H28F3N7
Cas No.2342583-66-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 120 mg/mL (268.16 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2346 mL11.1732 mL22.3464 mL111.7318 mL
5 mM0.4469 mL2.2346 mL4.4693 mL22.3464 mL
10 mM0.2235 mL1.1173 mL2.2346 mL11.1732 mL
20 mM0.1117 mL0.5587 mL1.1173 mL5.5866 mL
50 mM0.0447 mL0.2235 mL0.4469 mL2.2346 mL
100 mM0.0223 mL0.1117 mL0.2235 mL1.1173 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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