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NMI 8739
Catalog No. T11079Cas No. 129024-87-9
Alias n-docosahexaenoyl dopamine, Dha-DA conjugate
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
NMI 8739
Catalog No. T11079Alias n-docosahexaenoyl dopamine, Dha-DA conjugateCas No. 129024-87-9
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $77 | In Stock | |
| 10 mg | $123 | In Stock | |
| 25 mg | $217 | In Stock | |
| 50 mg | $318 | In Stock | |
| 100 mg | $472 | In Stock | |
| 500 mg | $1,070 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $95 | In Stock |
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Purity:98.51%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release. |
| In vitro | NMI 8739 (2 μM) significantly inhibits IL-6 and CCL-20 release up to 49% and 37%, respectivel. NMI 8739 suppresses the production of PGE2 in a concentration-dependent manner with 25.3%, 75% reduction at doses of 100 nM and 1 μM, respectively[2]. |
| Alias | n-docosahexaenoyl dopamine, Dha-DA conjugate |
| Molecular Weight | 463.65 |
| Formula | C30H41NO3 |
| Cas No. | 129024-87-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 90 mg/mL (194.1 mM), Sonication is recommended. DMSO: 90 mg/mL (194.1 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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