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Oxotremorine M iodide

Catalog No. T12339Cas No. 3854-04-4
Alias Oxotremorine methiodide

Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.

Oxotremorine M iodide

Oxotremorine M iodide

Purity: 98.75%
Catalog No. T12339Alias Oxotremorine methiodideCas No. 3854-04-4
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
Pack SizePriceAvailabilityQuantity
10 mg$43In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:98.75%
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Product Introduction

Bioactivity
Description
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
In vitro
Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM). Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively[1]. Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents[2].
In vivo
In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens[4].
AliasOxotremorine methiodide
Chemical Properties
Molecular Weight322.19
FormulaC11H19IN2O
Cas No.3854-04-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (310.4 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1038 mL15.5188 mL31.0376 mL155.1879 mL
5 mM0.6208 mL3.1038 mL6.2075 mL31.0376 mL
10 mM0.3104 mL1.5519 mL3.1038 mL15.5188 mL
20 mM0.1552 mL0.7759 mL1.5519 mL7.7594 mL
50 mM0.0621 mL0.3104 mL0.6208 mL3.1038 mL
100 mM0.0310 mL0.1552 mL0.3104 mL1.5519 mL

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