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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $68 | In Stock | |
2 mg | $98 | In Stock | |
5 mg | $172 | In Stock | |
10 mg | $239 | In Stock | |
25 mg | $488 | In Stock | |
50 mg | $716 | In Stock | |
100 mg | $987 | In Stock | |
500 mg | $1,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $189 | In Stock |
Description | PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo). |
In vivo | PFE-360 (4 mg/kg and 7.5 mg/kg, orally, BID, 10-12 weeks) treatment effectively reduces the LRRK2-pSer935/total LRRK2 ratio. It has no significant adverse effects[1]. |
Alias | PF-06685360 |
Molecular Weight | 308.34 |
Formula | C16H16N6O |
Cas No. | 1527475-61-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 3.08 mg/mL (10 mM) ![]() | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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