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PRMT6-IN-3
PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.
Catalog No. T73185Cas No. 2890765-10-1
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Purity:99.71%
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PRMT6-IN-3
Catalog No. T73185Cas No. 2890765-10-1
PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $48 | In Stock | |
| 5 mg | $113 | In Stock | |
| 10 mg | $172 | In Stock | |
| 25 mg | $297 | In Stock | |
| 50 mg | $455 | In Stock | |
| 100 mg | $637 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells. |
| Targets&IC50 | PRMT6:192 nM |
| In vitro | PRMT6-IN-3 (compound 25) (0-40 μM; 72 h) significantly induces apoptosis of cancer cells in a dose-dependent manner. Among them, a concentration of 40 μM could induce apoptosis in 43.44% and 35.08% of HCC827 and MDA-MB-435 cells, respectively.[1] PRMT6-IN-3 (80 μM; 3-7 days) has anti-proliferative activity against HCC827 and MDA-MB-435 cells.[1] |
| Molecular Weight | 374.5 |
| Formula | C19H26N4O2S |
| Cas No. | 2890765-10-1 |
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (146.86 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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