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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $32 | In Stock | |
5 mg | $52 | In Stock | |
10 mg | $89 | In Stock | |
25 mg | $197 | In Stock | |
50 mg | $353 | In Stock | |
100 mg | $589 | In Stock | |
200 mg | $753 | In Stock | |
1 mL x 10 mM (in DMSO) | $58 | In Stock |
Description | RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM). |
In vitro | RIPGBM causes caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 and acting as a molecular switch. It reduces the formation of a prosurvival RIPK2/ TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex [1]. |
Molecular Weight | 428.45 |
Formula | C26H21FN2O3 |
Cas No. | 355406-76-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (70.02 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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