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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $64 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $455 | In Stock | |
100 mg | $672 | In Stock | |
500 mg | $1,430 | In Stock | |
1 mL x 10 mM (in DMSO) | $70 | In Stock |
Description | RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome. |
In vitro | RN-18, that antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G.?RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation.?RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome. |
Molecular Weight | 344.45 |
Formula | C23H24N2O |
Cas No. | 443639-96-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (159.67 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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