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SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $82 | In Stock | |
2 mg | $118 | In Stock | |
5 mg | $183 | In Stock | |
10 mg | $278 | In Stock | |
25 mg | $463 | In Stock | |
50 mg | $667 | In Stock | |
1 mL x 10 mM (in DMSO) | $136 | In Stock |
Description | SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells. |
In vitro | SMIP004 reduces the levels of positive cell cycle regulators upregulates cyclin-dependent kinase inhibitors. It also causes G1 arrest, inhibition of colony formation in soft agar, and cell death [2]. |
In vivo | In SCID mice, SMIP004 effectively inhibits the growth of prostate and breast cancer xenografts [2]. |
Molecular Weight | 205.3 |
Formula | C13H19NO |
Cas No. | 143360-00-3 |
Smiles | CCCCC1=CC(C)=C(NC(C)=O)C=C1 |
Relative Density. | 1.003 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (487.09 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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