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Strictosamide

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Purity:100%

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COA HPLC HNMR

Strictosamide

Catalog No. TN2239Cas No. 23141-25-5

Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.

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Pack Size	Price	Availability
1 mg	$57	In Stock
5 mg	$128	In Stock
10 mg	$190	In Stock
25 mg	$318	In Stock
50 mg	$469	In Stock
100 mg	$689	In Stock
1 mL x 10 mM (in DMSO)	$140	In Stock

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Product Introduction

Bioactivity

Description

Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.

In vitro

At 20 and 40 mg/kg, strictosamide obviously decreased the TPA-induced mice ear edema (24.7 and 28.1% inhibition, respectively), and significantly inhibited acetic acid-stimulated peritoneal vascular permeability in mice (23.3 and 33.4% inhibition, respectively).?It also significantly decreased the leukocytes in the mice peritoneal cavity induced by CMC-Na at all the tested doses (46.0, 49.1, and 58.7% inhibition, respectively).?To acetic acid-induced writhing test in mice, strictosamide markedly prolonged the pain latency at 20 and 40 mg/kg and decreased the writhing counts at 40 mg/kg (49.7% inhibition).?However, it did not obviously improve the pain threshold of mice in hot-plate test[2].

Chemical Properties

Molecular Weight	498.52
Formula	C26H30N2O8
Cas No.	23141-25-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (45.13 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0059 mL	10.0297 mL	20.0594 mL	100.2969 mL
5 mM	0.4012 mL	2.0059 mL	4.0119 mL	20.0594 mL
10 mM	0.2006 mL	1.0030 mL	2.0059 mL	10.0297 mL
20 mM	0.1003 mL	0.5015 mL	1.0030 mL	5.0148 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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