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UNC6934

Catalog No. T9584Cas No. 2561494-77-5

UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.

UNC6934

UNC6934

Purity: 99.81%
Catalog No. T9584Cas No. 2561494-77-5
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
Pack SizePriceAvailabilityQuantity
1 mg$78In Stock
2 mg$113In Stock
5 mg$189In Stock
10 mg$297In Stock
25 mg$479In Stock
50 mg$679In Stock
100 mg$928In Stock
500 mg$1,850In Stock
1 mL x 10 mM (in DMSO)$198In Stock
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Purity:99.81%
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Product Introduction

Bioactivity
Description
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
In vitro
UNC6934 occupies the canonical H3K36me2-binding pocket of PWWP1, antagonizes PWWP1 interaction with nucleosomal H3K36me2 and selectively engages endogenous NSD2 in cells[1].
Chemical Properties
Molecular Weight443.45
FormulaC24H21N5O4
Cas No.2561494-77-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (45.10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2550 mL11.2752 mL22.5505 mL112.7523 mL
5 mM0.4510 mL2.2550 mL4.5101 mL22.5505 mL
10 mM0.2255 mL1.1275 mL2.2550 mL11.2752 mL
20 mM0.1128 mL0.5638 mL1.1275 mL5.6376 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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