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YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $35 | In Stock | |
10 mg | $43 | In Stock | |
25 mg | $93 | In Stock | |
50 mg | $129 | In Stock | |
100 mg | $167 | In Stock | |
200 mg | $247 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity. |
Targets&IC50 | HIV:8.4 μM |
In vitro | YYA-021 enhances the neutralization sensitivity of simian-human immunodeficiency virus (SHIV) carrying the envelope from the clade B clinical human immunodeficiency virus type 1 (HIV-1) isolate MNA. [1] |
In vivo | In rats and rhesus macaques, YYA-021 (i.v.) shows moderate half-lives, wide tissue distribution and relatively high distribution volumes. [2] |
Alias | YYA 021 |
Molecular Weight | 317.43 |
Formula | C18H27N3O2 |
Cas No. | 144217-65-2 |
Smiles | Cc1ccc(NC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)cc1 |
Relative Density. | 1.11 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (34.65 mM), Sonication is recommended. H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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