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5-Carboxamidotryptamine maleate

Catalog No. T22520 CAS 74885-72-6

Synonyms: 5-CT maleate

5-Carboxamidotryptamine maleate (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.

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5-Carboxamidotryptamine maleate, CAS 74885-72-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	5-Carboxamidotryptamine maleate (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.
Targets&IC50	AmOct-α2R-HA:0.00416 μM
In vivo	Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats[1].
Animal Research	Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats

Synonyms	5-CT maleate
Molecular Weight	319.31
Formula	C15H17N3O5
CAS No.	74885-72-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: <31.93mg/ml

DMSO: 45.0 mg/mL (140.9 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Jun Yamada, et, al.Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats. European Journal of Pharmacology.Volume 359, Issue 1, 16 October 1998, Pages 81-86

Dose Conversion

You can also refer to dose conversion for different animals. More

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

5-Carboxamidotryptamine maleate 74885-72-6 GPCR/G Protein Neuroscience 5-HT Receptor 5-CT maleate Inhibitor inhibitor inhibit

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