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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $39 | In Stock | |
25 mg | $62 | In Stock | |
50 mg | $91 | In Stock | |
100 mg | $133 | In Stock | |
200 mg | $198 | In Stock |
Description | Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain. |
In vitro | Amitriptyline inhibits both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline is also an inhibitor of histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. |
Molecular Weight | 277.4 |
Formula | C20H23N |
Cas No. | 50-48-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
Solubility Information | H2O: 9.7 mg/mL (34.96 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
H2O
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