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BMS-1

Catalog No. T3655Cas No. 1675201-83-8
Alias PD1-PDL1 inhibitor 1, PD-1/PD-L1 inhibitor 1

BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

BMS-1

BMS-1

Purity: 99.86%
Catalog No. T3655Alias PD1-PDL1 inhibitor 1, PD-1/PD-L1 inhibitor 1Cas No. 1675201-83-8
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
2 mg$70In Stock
5 mg$112In Stock
10 mg$187In Stock
25 mg$350In Stock
50 mg$503In Stock
100 mg$733In Stock
500 mg$1,530In Stock
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Purity:99.86%
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Product Introduction

Bioactivity
Description
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
Targets&IC50
PD-1/PD-L1:0.006 μM
AliasPD1-PDL1 inhibitor 1, PD-1/PD-L1 inhibitor 1
Chemical Properties
Molecular Weight475.58
FormulaC29H33NO5
Cas No.1675201-83-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.76 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1027 mL10.5135 mL21.0270 mL105.1348 mL
5 mM0.4205 mL2.1027 mL4.2054 mL21.0270 mL
10 mM0.2103 mL1.0513 mL2.1027 mL10.5135 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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