Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 179.00 | |
2 mg | In stock | $ 269.00 | |
5 mg | In stock | $ 455.00 | |
10 mg | In stock | $ 657.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,830.00 | |
500 mg | In stock | $ 3,690.00 |
Description | DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA. |
In vitro | DPBQ induces apoptosis and death and selectively affects 4N cells.DPBQ can specifically induce the expression and phosphorylation of p53.Deletion of TP53 can restore the proliferation of tetraploid cells in the presence of DPBQ. |
Synonyms | ZINC1620467, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione |
Molecular Weight | 362.38 |
Formula | C24H14N2O2 |
CAS No. | 7029-89-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.5 mg/mL (6.9 mM), Sonification and heating to 80℃ are recommended.
You can also refer to dose conversion for different animals. More
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DPBQ 7029-89-2 Apoptosis p53 ZINC-1620467 ZINC1620467 ZINC 1620467 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione inhibitor inhibit