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GAK inhibitor 49

Catalog No. T8535Cas No. 319492-82-5

GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).

GAK inhibitor 49

GAK inhibitor 49

Purity: 99.93%
Catalog No. T8535Cas No. 319492-82-5
GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
5 mg$119In Stock
10 mg$197In Stock
25 mg$332In Stock
50 mg$478In Stock
100 mg$653In Stock
200 mg$879In Stock
1 mL x 10 mM (in DMSO)$137In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).
Chemical Properties
Molecular Weight370.4
FormulaC20H22N2O5
Cas No.319492-82-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 12 mg/mL (32.4 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6998 mL13.4989 mL26.9978 mL134.9892 mL
5 mM0.5400 mL2.6998 mL5.3996 mL26.9978 mL
10 mM0.2700 mL1.3499 mL2.6998 mL13.4989 mL
20 mM0.1350 mL0.6749 mL1.3499 mL6.7495 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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