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GNE-3511

GNE-3511
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
Catalog No. T3707Cas No. 1496581-76-0
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Purity:99.37%
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GNE-3511

Purity: 99.37%
Catalog No. T3707Alias GNE3511Cas No. 1496581-76-0

GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$43In Stock
25 mg$73In Stock
50 mg$118In Stock
100 mg$197In Stock
1 mL x 10 mM (in DMSO)$47In Stock
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Product Introduction

Bioactivity
Description
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
Targets&IC50
DLK:0.5 nM. (Ki)
AliasGNE3511
Chemical Properties
Molecular Weight440.49
FormulaC23H26F2N6O
Cas No.1496581-76-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6.25 mg/mL (14.19 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2702 mL11.3510 mL22.7020 mL113.5100 mL
5 mM0.4540 mL2.2702 mL4.5404 mL22.7020 mL
10 mM0.2270 mL1.1351 mL2.2702 mL11.3510 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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