Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 76.00 | |
25 mg | In stock | $ 168.00 | |
50 mg | In stock | $ 306.00 | |
100 mg | In stock | $ 438.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM). |
Targets&IC50 | Wnt:0.2 μM(EC50) |
In vivo | In the Wnt pathway, IWR-1 interacts with Axin to exert a reversible inhibitory effect. |
Synonyms | IWR-1-endo, endo-IWR 1 |
Molecular Weight | 409.44 |
Formula | C25H19N3O3 |
CAS No. | 1127442-82-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40.9 mg/mL (100 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
IWR-1 1127442-82-3 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin Inhibitor IWR-1-endo inhibit endo-IWR 1 Wnt IWR1 IWR 1 inhibitor