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ML-099
🥰Excellent
Catalog No. T22991Cas No. 496775-95-2
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
ML-099
🥰Excellent
Purity: 99.48%
Catalog No. T22991Cas No. 496775-95-2
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $41 | In Stock | |
| 2 mg | $58 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $155 | In Stock | |
| 25 mg | $322 | In Stock | |
| 50 mg | $513 | In Stock | |
| 100 mg | $747 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $95 | In Stock |
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Purity:99.48%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | pan activator of Ras-related GTPases |
| Targets&IC50 | Rac1:20.17 nM(wild type,EC50), Rac1:25.42 nM(activated mutant,EC50), Cell division cycle 42:100 nM(wild type,EC50), Cell division cycle 42:58.88 nM(activated mutant,EC50), Ras:95.5 nM(activated mutant,EC50) |
| In vitro | ML-099 activates Ras protein wild type(EC50 = 141.25 nM), Rab7(EC50 = 181.97 nM), Rab-2A(EC50 = 354.81 nM), Rac1 protein activated mutant(EC50 = 25.42 nM), Rac1 protein wild type(EC50 = 20.17 nM), Ras protein activated mutant(EC50 = 95.5 nM), cell division cycle 42 activated mutant(EC50 = 58.88 nM) and cell division cycle 42 wild type(EC50 = 100 nM)[1]. |
| Molecular Weight | 259.32 |
| Formula | C14H13NO2S |
| Cas No. | 496775-95-2 |
| Smiles | OC(=O)c1cccnc1SCCc1ccccc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (192.81 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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