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ML348

Catalog No. T3439Cas No. 899713-86-1
Alias GNF-Pf-1127

ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.

ML348

ML348

Purity: 99.88%
Catalog No. T3439Alias GNF-Pf-1127Cas No. 899713-86-1
ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.
Pack SizePriceAvailabilityQuantity
2 mg$39In Stock
5 mg$63In Stock
10 mg$98In Stock
25 mg$239In Stock
50 mg$372In Stock
100 mg$597In Stock
200 mg$833In Stock
500 mg$1,260In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM.
Targets&IC50
LYPLA1:210 nM
AliasGNF-Pf-1127
Chemical Properties
Molecular Weight415.79
FormulaC18H17ClF3N3O3
Cas No.899713-86-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 83.33 mg/mL (200.41 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4051 mL12.0253 mL24.0506 mL120.2530 mL
5 mM0.4810 mL2.4051 mL4.8101 mL24.0506 mL
10 mM0.2405 mL1.2025 mL2.4051 mL12.0253 mL
20 mM0.1203 mL0.6013 mL1.2025 mL6.0127 mL
50 mM0.0481 mL0.2405 mL0.4810 mL2.4051 mL
100 mM0.0241 mL0.1203 mL0.2405 mL1.2025 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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