Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 39.00 | |
25 mg | In stock | $ 66.00 | |
50 mg | In stock | $ 97.00 | |
100 mg | In stock | $ 155.00 | |
500 mg | In stock | $ 389.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation. |
Targets&IC50 | PPARγ:17.7 μM (EC50), RXRα:10.4 μM (EC50) |
In vitro | Magnolol shows significant inhibitory activities against Trichophyton mentagrophytes, Microsporium gypseum, Epidermophyton floccosum, Aspergillus niger, Cryptococcus neoformans, and Candida albicans with minimum inhibitory concentrations (MIC) in a range of 25-100 μg/ml. |
Source |
Synonyms | NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol |
Molecular Weight | 266.33 |
Formula | C18H18O2 |
CAS No. | 528-43-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 49 mg/mL (184 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 49 mg/mL (184 mM)
You can also refer to dose conversion for different animals. More
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Magnolol 528-43-8 Apoptosis Autophagy DNA Damage/DNA Repair Metabolism Microbiology/Virology NF-Κb Antibacterial PPAR Retinoid Receptor NF-κB p53 inhibit RAR/RXR Retinoic acid receptors NSC 293099 NSC-293099 Retinoid X receptors 5,5'-Diallyl-2,2'-biphenyldiol NSC293099 Inhibitor Peroxisome proliferator-activated receptors Bacterial inhibitor