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Methyl rosmarinate

Catalog No. TN1928 CAS 99353-00-1

Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).

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Methyl rosmarinate, CAS 99353-00-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 79.00
5 mg	In stock	$ 193.00
10 mg	In stock	$ 328.00
25 mg	In stock	$ 553.00
50 mg	In stock	$ 789.00
100 mg	In stock	$ 1,070.00
1 mL * 10 mM (in DMSO)	In stock	$ 216.00

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Purity: 99.62%

Purity: 97.52%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
Targets&IC50	Tyrosinase:0.28 mM
In vitro	An initial microtiter dilution assay indicated activity of compounds against S. carnosus LTH1502, whereas esters with chain lengths, RA, n-Methyl rosmarinate (RE1), n-dodecyl rosmarinate (RE12), and n-octadecyl rosmarinate (RE18) were used in a time-kill assay S. carnosus LTH1502. Compounds were added at 0.75 mM in the log phase, 5 mM in the exponential phase, 10 mM in the stationary phase. RA had no effect in the lag and exponential phase but decreased cell counts during the stationary phase. In contrast, RE1 and RE12 decreased cell number in all three phase, will RE12 reducing counts most rapidly. Addition of RE18 did not affect regardless of the growth phase[1]
Source	Natural Products > Lamiaceae > Rosmarinus

Molecular Weight	374.34
Formula	C19H18O8
CAS No.	99353-00-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 74.88 mg/mL (200 mM ), Sonication is recommended.

References and Literature

1. Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263.J Food Prot. 2013 Sep;76(9):1539-48.

Related compound libraries

This product is contained In the following compound libraries：

Miao medicine Compound Library Inhibitor Library Tobacco Monomer Library Anti-Gastroenteritis Natural Product Library Anti-Tumor Natural Product Library Selected Plant-Sourced Compound Library Anti-Fungal Compound Library Traditional Mongolian Medicine Compound Library Polyphenolic Natural Product Library Anti-Pancreatic Cancer Compound Library

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Keywords

Methyl rosmarinate 99353-00-1 Microbiology/Virology Proteases/Proteasome MMP Anti-infection Tyrosinase Inhibitor inhibit inhibitor

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