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Mobocertinib

Catalog No. T8151   CAS 1847461-43-1
Synonyms: tak788

Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Mobocertinib Chemical Structure
Mobocertinib, CAS 1847461-43-1
Pack Size Availability Price/USD Quantity
5 mg In stock $ 30.00
10 mg In stock $ 47.00
25 mg In stock $ 72.00
50 mg In stock $ 122.00
100 mg In stock $ 198.00
500 mg In stock $ 515.00
1 mL * 10 mM (in DMSO) In stock $ 44.00
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Purity: 99.72%
Purity: 99.09%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
Targets&IC50 EGFR (wt):35 nM (IC50)
Synonyms tak788
Molecular Weight 585.7
Formula C32H39N7O4
CAS No. 1847461-43-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5.86 mg/mL (10 mM)

TargetMolReferences and Literature

1. Landon J. DURAK, et al. Pharmaceutical salts of pyrimidine derivatives and method of treating disorders. WO2019222093A1.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Tyrosine Kinase Inhibitor Library Approved Drug Library Anti-Ovarian Cancer Compound Library Anti-Breast Cancer Compound Library Anti-Lung Cancer Compound Library Clinical Compound Library

Related Products

Related compounds with same targets
BKI-1369 Vandetanib EGFR-IN-76 Protopine hydrochloride Patritumab PD-089828 Petosemtamab Rilzabrutinib

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Mobocertinib 1847461-43-1 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR AP-32788 Epidermal growth factor receptor TAK-788 H1975 Inhibitor HCC827 inhibit CUTO14 ErbB-1 TAK 788 A431 HCC4011 EGFRex20ins AP32788 NSCLC LU0387 tak788 HER1 AP 32788 inhibitor

 

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