Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 47.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 147.00 | |
50 mg | In stock | $ 218.00 | |
100 mg | In stock | $ 323.00 | |
200 mg | In stock | $ 483.00 | |
500 mg | In stock | $ 776.00 |
Description | NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities. |
Kinase Assay | Assay of PKC Activity : Assay mixtures contain 0.2 mg/mL peptide-gamma, 10 μM MgCl2, 0.6 mM CaCl2, 10 μM [γ-32P]ATP, 1.25 mg/mL phosphatidylserine and 1.25 ng/mL phorbol 12-myristate 13-acetate in 20 mM Hepes (pH 7.5), 2 mM EDTA, 1 mM dithiothreitol and 0.02% (w/v) Triton X-100. Peptide-γ is a synthetic peptide, GPRPLFCRKGSLRQKW, resembling the PKC-γ pseudosubstrate site, except that a serine residue replaces the pseudosubstrate alanine, converting the peptide from an inhibitor into a substrat. The assays are started by the addition of 2.5 m-units of enzyme, incubated at 30 °C for 10 min and terminated by spotting on to P81 paper, followed by extensive washing in 75 mM orthophosphoric acid. The papers are then washed in ethanol, dried, and incorporated radioactivity is determined by liquidscintillation spectroscopy. |
Molecular Weight | 383.27 |
Formula | C20H16Cl2N4 |
CAS No. | 140926-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. More
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RE-640 140926-75-6 Immunology/Inflammation Microbiology/Virology Parasite CCR inhibit NSC5844 NSC-5844 RE640 Inhibitor RE 640 NSC 5844 inhibitor