Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 32.00 | |
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 142.00 | |
50 mg | In stock | $ 228.00 | |
100 mg | In stock | $ 393.00 | |
200 mg | In stock | $ 511.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ. |
Targets&IC50 | PI3Kγ:23 nM, PI3Kα:39 nM, PI3Kβ:383 nM, PI3Kδ:36 nM |
Cell Research | Cells including BT474, HCC1937 et al. are seeded in 100-mm dishes in media containing 2.5% FBS with or without XL147. After 3 days, detached and adherent cells are pooled, ?xed, and labeled with propidium iodide by using the APO-BrdU kit. Labeled cells are analyzed using the Becton Dickinson FACSCalibur system. (Only for Reference) |
Synonyms | XL147 analogue, SAR245408 |
Molecular Weight | 448.52 |
Formula | C21H16N6O2S2 |
CAS No. | 956958-53-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 22.45 mg/mL(50.1 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Pilaralisib analogue 956958-53-5 Apoptosis DNA Damage/DNA Repair PI3K/Akt/mTOR signaling DNA-PK PI3K SAR-245408 Inhibitor XL147 analogue inhibit Phosphoinositide 3-kinase SAR 245408 SAR245408 inhibitor