Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 77.00 | |
10 mg | In stock | $ 101.00 | |
25 mg | In stock | $ 190.00 | |
50 mg | In stock | $ 343.00 | |
100 mg | In stock | $ 531.00 | |
500 mg | In stock | $ 1,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. |
In vitro | In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. [1] |
In vivo | In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%. [1] |
Synonyms | SBC115076 |
Molecular Weight | 527.61 |
Formula | C31H33N3O5 |
CAS No. | 489415-96-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (176.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SBC-115076 489415-96-5 Cell Cycle/Checkpoint Metabolism Others Serine/threonin kinase Inhibitor inhibit sensitivity Ser/Thr Protease LDL HFD-fed obesity Serine proteases rats SBC115076 SBC 115076 Threonine proteases Serine endopeptidases insulin inhibitor