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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $32 | In Stock | |
2 mg | $46 | In Stock | |
5 mg | $80 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $198 | In Stock | |
50 mg | $316 | In Stock | |
100 mg | $538 | In Stock | |
1 mL x 10 mM (in DMSO) | $68 | In Stock |
Description | SSD114 is a novel GABAB receptor positive allosteric modulator. |
In vivo | Pretreatment with SSD114 hydrochloride significantly influences the onset and duration of loss of righting reflex (LORR) in mice. Statistical analysis reveals that SSD114 hydrochloride effectively reduces the onset of LORR [F(5,30)=4.55, P<0.005], with post hoc analysis demonstrating a notably quicker onset in mice pretreated with doses of 10 mg/kg or higher, compared to those treated with a vehicle. Furthermore, the duration of LORR is extended following pretreatment with SSD114 hydrochloride [F(5,30)=4.81, P<0.005], with post hoc analysis showing a significant increase in LORR duration in mice pretreated with 10 and 100 mg/kg doses when compared to vehicle-treated mice [1]. |
Molecular Weight | 387.83 |
Formula | C18H21ClF3N3O |
Cas No. | 2319790-02-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (116.03 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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