Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 163.00 | |
10 mg | In stock | $ 245.00 | |
25 mg | In stock | $ 415.00 | |
50 mg | In stock | $ 617.00 | |
100 mg | In stock | $ 877.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 196.00 |
Description | SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively. |
Targets&IC50 | RON:9 nM, c-Met:4 nM |
Synonyms | RON-IN-1, AMG-1 |
Molecular Weight | 556.58 |
Formula | C31H29FN4O5 |
CAS No. | 913376-84-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (161.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SYN1143 913376-84-8 Tyrosine Kinase/Adaptors c-Met/HGFR SYN-1143 RON-IN-1 tumor RON dual inhibit AMG 1 SYN 1143 cancer AMG1 Inhibitor c-Met AMG-1 inhibitor