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Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $89 | In Stock | |
10 mg | Inquiry | In Stock | |
25 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $248 | In Stock |
Description | Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65. |
In vivo | Valinomycin is irritating in contact with eyes and skin. Inhalation of Valinomycin can cause respiratory disturbances and even loss of consciousness. The median lethal dose (LD50) of Valinomycin in mice and rabbits was 2.5 mg/kg and 5 mg/kg, respectively. Valinomycin also has various chronic effects, including central and peripheral nervous system damage, eye damage, lens damage, and corneal damage [3]. |
Alias | NSC 122023 |
Molecular Weight | 1111.32 |
Formula | C54H90N6O18 |
Cas No. | 2001-95-8 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 40 mg/mL (36 mM), Sonication is recommended. DMSO: 20 mg/mL (18 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO/Ethanol
Ethanol
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