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Verdiperstat

Catalog No. T5463 CAS 890655-80-8

Synonyms: AZD3241, AZD 3241

Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

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Verdiperstat, CAS 890655-80-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 32.00
2 mg	In stock	$ 45.00
5 mg	In stock	$ 72.00
10 mg	In stock	$ 122.00
25 mg	In stock	$ 222.00
50 mg	In stock	$ 369.00
100 mg	In stock	$ 571.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.16%

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Description	Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
Targets&IC50	Myeloperoxidase:630 nM
In vitro	Verdiperstat (AZD3241) functions as a myeloperoxidase (MPO) inhibitor, demonstrating potency with an IC50 value of 630 nM. It is primarily utilized in the study of neurodegenerative brain disorders[1]. By selectively and irreversibly targeting MPO, Verdiperstat (AZD3241) potentially reduces oxidative stress, consequently diminishing prolonged neuroinflammation.

Synonyms	AZD3241, AZD 3241
Molecular Weight	253.32
Formula	C11H15N3O2S
CAS No.	890655-80-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 150 mg/mL (592.14 mM)

References and Literature

1. Johnström P, et al. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nucl Med Biol. 2015 Jun;42(6):555-60.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Highly Selective Inhibitor Library Inhibitor Library Bioactive Compound Library Glutamine Metabolism Compound Library ReFRAME Related Library Oxidation-Reduction Compound Library Antioxidant Compound Library NO PAINS Compound Library Anti-Metabolism Disease Compound Library

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Related compounds with same targets

Tinoridine hydrochloride AZD5904 Ezatiostat hydrochloride PF-06282999 NBDHEX ML-210 GSTO1-IN-1 Cefdinir

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Verdiperstat 890655-80-8 Metabolism Glutathione Peroxidase inhibit AZD-3241 AZD3241 Inhibitor AZD 3241 inhibitor

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