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AMG131

Catalog No. T8780Cas No. 315224-26-1
Alias INT-131, CHS 131, AMG-131

AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes)

AMG131

AMG131

Purity: 98.01%
Catalog No. T8780Alias INT-131, CHS 131, AMG-131Cas No. 315224-26-1
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes)
Pack SizePriceAvailabilityQuantity
1 mg$35In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$263In Stock
50 mg$428In Stock
100 mg$639In Stock
1 mL x 10 mM (in DMSO)$82In Stock
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Purity:98.01%
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Product Introduction

Bioactivity
Description
AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes)
AliasINT-131, CHS 131, AMG-131
Chemical Properties
Molecular Weight514.21
FormulaC21H12Cl4N2O3S
Cas No.315224-26-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (53.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9447 mL9.7237 mL19.4473 mL97.2365 mL
5 mM0.3889 mL1.9447 mL3.8895 mL19.4473 mL
10 mM0.1945 mL0.9724 mL1.9447 mL9.7237 mL
20 mM0.0972 mL0.4862 mL0.9724 mL4.8618 mL
50 mM0.0389 mL0.1945 mL0.3889 mL1.9447 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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