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Amoxicillin trihydrate

Amoxicillin trihydrate
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Purity:99.09%
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Amoxicillin trihydrate

Catalog No. T1005LCas No. 61336-70-7
Amoxicillin trihydrate (Moxaline trihydrate) binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Amoxicillin trihydrate is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.
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Pack SizePriceAvailabilityQuantity
500 mg$42In Stock
1 g$50In Stock
1 mL x 10 mM (in DMSO)$46In Stock
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Product Introduction

Bioactivity
Description
Amoxicillin trihydrate (Moxaline trihydrate) binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Amoxicillin trihydrate is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.
In vivo
A 25 microliter volume of a 1-% L-epinephrine borate solution applied on the cornea of one eye in 12 monkeys reduces blood flow through the iris and the ciliary body by 59% and 20%, respectively, compared to the untreated control eyes[1]. Epinephrine is a direct-acting sympathomimetic α-adrenergic and β-adrenergic agonist with cyclic adenosine monophosphate-mediated, complex, bidirectional pharmacologic effects on many target organs[2]. In young adult rats, endogenous release of epinephrine facilitates stable memory formation for temporally associated events. Epinephrine enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory[3]. Epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Epinephrine increases arterial blood pressure and coronary perfusion during CPR via alpha-1-adrenoceptor agonist effects[4].
AliasAmoxycillin trihydrate, Amoxil trihydrate, Amoxipen trihydrate, Moxaline trihydrate
Chemical Properties
Molecular Weight419.45
FormulaC16H25N3O8S
Cas No.61336-70-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (143.04 mM)
H2O: 1.25 mg/mL (2.98 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.3841 mL11.9204 mL23.8407 mL119.2037 mL
DMSO
1mg5mg10mg50mg
5 mM0.4768 mL2.3841 mL4.7681 mL23.8407 mL
10 mM0.2384 mL1.1920 mL2.3841 mL11.9204 mL
20 mM0.1192 mL0.5960 mL1.1920 mL5.9602 mL
50 mM0.0477 mL0.2384 mL0.4768 mL2.3841 mL
100 mM0.0238 mL0.1192 mL0.2384 mL1.1920 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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