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Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco, acting as a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. It depolarizes TE671 cells that endogenously express human myotypic nAChRs.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $38 | In Stock | |
50 mg | Inquiry | In Stock | |
1 mL x 10 mM (in DMSO) | $30 | In Stock |
Description | Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco, acting as a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. It depolarizes TE671 cells that endogenously express human myotypic nAChRs. |
In vivo | Anabasine significantly reverses impairment at doses of 0.2 mg/kg (p<0.05) and 2 mg/kg (p<0.025), without any significant effects on response latency when administered alone. However, the 0.06 mg/kg Anabasine dose exacerbates dizocilpine-induced impairment, increasing non-response trials significantly (p<0.05), and none of the Anabasine doses affect choice accuracy on their own [2]. |
Alias | (S)-Anabasine, (-)-Anabasine |
Molecular Weight | 162.23 |
Formula | C10H14N2 |
Cas No. | 494-52-0 |
Smiles | C1CC[C@H](NC1)c1cccnc1 |
Relative Density. | 1.0455 g/cm3 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (308.20 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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