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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $51 | In Stock | |
2 mg | $74 | In Stock | |
5 mg | $122 | In Stock | |
10 mg | $178 | In Stock | |
25 mg | $293 | In Stock | |
50 mg | $413 | In Stock | |
100 mg | $547 | In Stock | |
1 mL x 10 mM (in DMSO) | $172 | In Stock |
Description | Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization. |
In vitro | Ansamitocin p-3 inhibits the proliferation in a concentration-dependent manner with IC50s of 20, 50, 140, and 150 pM for MCF-7, HeLa, EMT-6/AR1, and MDA-MB-231 cells in culture, respectively. Ansamitocin P3 binds to purified tubulin (Kd = 1.3 µM)[1]. |
Alias | Maytansinol isobutyrate, Antibiotic C 15003P3, NSC292222 |
Molecular Weight | 635.14 |
Formula | C32H43ClN2O9 |
Cas No. | 66584-72-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90.0 mg/mL (141.7 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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