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Azoramide

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Purity:99.85%

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COA HNMR HPLC

Azoramide

Catalog No. T4304Cas No. 932986-18-0

Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.

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Pack Size	Price	Availability
5 mg	$43	In Stock
10 mg	$52	In Stock
25 mg	$101	In Stock
50 mg	$158	In Stock
100 mg	$288	In Stock
500 mg	$693	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Product Introduction

Bioactivity

Description	Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
In vitro	Azoramide, a dual-function endoplasmic reticulum (ER) modulator, improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems.
In vivo	In two independent mouse models of obesity, Azoramide exhibits potent antidiabetic efficacy by improving insulin sensitivity and pancreatic β cell function.

Chemical Properties

Molecular Weight	308.83
Formula	C15H17ClN2OS
Cas No.	932986-18-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (161.91 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2380 mL	16.1901 mL	32.3803 mL	161.9014 mL
5 mM	0.6476 mL	3.2380 mL	6.4761 mL	32.3803 mL
10 mM	0.3238 mL	1.6190 mL	3.2380 mL	16.1901 mL
20 mM	0.1619 mL	0.8095 mL	1.6190 mL	8.0951 mL
50 mM	0.0648 mL	0.3238 mL	0.6476 mL	3.2380 mL
100 mM	0.0324 mL	0.1619 mL	0.3238 mL	1.6190 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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