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Azumolene
🥰Excellent
Catalog No. T8815Cas No. 64748-79-4
Alias EU4093 free base
Azumolene (EU4093 free base)
Azumolene
🥰Excellent
Purity: 98.35%
Catalog No. T8815Alias EU4093 free baseCas No. 64748-79-4
Azumolene (EU4093 free base)
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $42 | In Stock | |
| 5 mg | $67 | In Stock | |
| 10 mg | $118 | In Stock | |
| 25 mg | $247 | In Stock | |
| 50 mg | $392 | In Stock | |
| 100 mg | $592 | In Stock | |
| 500 mg | $1,280 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $75 | In Stock |
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Purity:98.35%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Azumolene (EU4093 free base) |
| In vivo | Azumolene is a direct acting, skeletal muscle relaxant with structural similarities to dantrolene sodium in that the para-nitro phenyl group of dantrolene sodium is replaced by a para-bromo phenyl group.2.The effect of Azumolene on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg kg-1.This dose of Azumolene reduces the amplitude of the twitch to 31.9% of the control value.By comparison, dantrolene sodium reduced the twitch amplitude to 31.3% of the control value at a dose of 5 mg kg-1.3.The contraction of intrafusal muscle as measured by the response of spindle afferent discharge was also reduced by Azumolene.4.The most significant difference between the effect of Azumolene and dantrolene sodium on the contraction of intrafusal muscle was that Azumolene had an appreciable depressant action at high stimulation frequencies at which dantrolene sodium had only a minimal relaxant effect on the intrafusal muscle contraction. |
| Alias | EU4093 free base |
| Molecular Weight | 349.14 |
| Formula | C13H9BrN4O3 |
| Cas No. | 64748-79-4 |
| Smiles | Brc1ccc(cc1)-c1cnc(\C=N\N2CC(=O)NC2=O)o1 |
| Relative Density. | 1.79g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (128.89 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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