Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

BMT-124110 Formate

Catalog No. T10572L
Alias BMT-124110 Formate(1679371-59-5 Free base)

BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.

BMT-124110 Formate

BMT-124110 Formate

Purity: 99.17%
Catalog No. T10572LAlias BMT-124110 Formate(1679371-59-5 Free base)
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
Pack SizePriceAvailabilityQuantity
1 mg$195In Stock
5 mg$430In Stock
10 mg$636In Stock
25 mg$987In Stock
50 mg$1,360In Stock
100 mg$1,830In Stock
500 mg$3,680In Stock
1 mL x 10 mM (in DMSO)$449In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "BMT-124110 Formate"

Select Batch
Purity:99.17%
ee:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
Targets&IC50
BIKE:17 nM, AAK1 (cells):3.2±1.4, GAK:99 nM, AAK1:0.9 nM
In vitro
BMT-124110 exhibits a cellular IC50 of 3.2±1.4 nM against AAK1.[1]
In vivo
BMT-124110 (30 mM; pH 4; 110–30 nA; 3 minutes; naive male rats) is added directly onto the spinal covered by micro iontophoresis, leading to a reduction in windup-induced activity in 10/14 animals.[1]
AliasBMT-124110 Formate(1679371-59-5 Free base)
Chemical Properties
Molecular Weight344.41
FormulaC22H20N2O2
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 4.15 mg/mL (10 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9035 mL14.5176 mL29.0352 mL145.1758 mL
5 mM0.5807 mL2.9035 mL5.8070 mL29.0352 mL
10 mM0.2904 mL1.4518 mL2.9035 mL14.5176 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy BMT-124110 Formate | purchase BMT-124110 Formate | BMT-124110 Formate cost | order BMT-124110 Formate | BMT-124110 Formate chemical structure | BMT-124110 Formate in vivo | BMT-124110 Formate in vitro | BMT-124110 Formate formula | BMT-124110 Formate molecular weight