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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $108 | In Stock | |
10 mg | $158 | In Stock | |
25 mg | $266 | In Stock | |
50 mg | $395 | In Stock | |
100 mg | $587 | In Stock | |
500 mg | $1,280 | In Stock | |
1 mL x 10 mM (in DMSO) | $133 | In Stock |
Description | CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells. |
In vitro | The left phenyl group is situated within a hydrophobic pocket formed by various amino acids. The predicted binding mode of CCT129957 exhibits a robust hydrogen bonding pattern and hydrophobic contacts[1].CCT129957 inhibits the growth of renal UO-31 and breast T-47D cancer cells by approximately 60-70%[2]. |
Molecular Weight | 309.32 |
Formula | C17H15N3O3 |
Cas No. | 883098-58-6 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (161.64 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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