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CCT129957
🥰Excellent
Catalog No. T14903Cas No. 883098-58-6
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
CCT129957
🥰Excellent
Purity: 99.44%
Catalog No. T14903Cas No. 883098-58-6
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $39 | In Stock | |
| 5 mg | $89 | In Stock | |
| 10 mg | $135 | In Stock | |
| 25 mg | $245 | In Stock | |
| 50 mg | $367 | In Stock | |
| 100 mg | $552 | In Stock | |
| 500 mg | $1,170 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $98 | In Stock |
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Purity:99.44%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells. |
| Targets&IC50 | PLCγ:3 μM |
| In vitro | The left phenyl group is situated within a hydrophobic pocket formed by various amino acids. The predicted binding mode of CCT129957 exhibits a robust hydrogen bonding pattern and hydrophobic contacts[1].CCT129957 inhibits the growth of renal UO-31 and breast T-47D cancer cells by approximately 60-70%[2]. |
| Molecular Weight | 309.32 |
| Formula | C17H15N3O3 |
| Cas No. | 883098-58-6 |
| Smiles | [O-][N+](=O)c1cccc2cc([nH]c12)C(=O)NCCc1ccccc1 |
| Relative Density. | 1.337 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (161.64 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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