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CHPG hydrochloride
Catalog No. T10809L
Alias CHPG hydrochloride(170846-74-9 Free base)
CHPG hydrochloride is a selective agonist of mGluR5.
CHPG hydrochloride
Catalog No. T10809LAlias CHPG hydrochloride(170846-74-9 Free base)
CHPG hydrochloride is a selective agonist of mGluR5.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $85 | In Stock | |
| 5 mg | $197 | In Stock | |
| 10 mg | $295 | In Stock | |
| 25 mg | $472 | In Stock | |
| 50 mg | $672 | In Stock | |
| 100 mg | $894 | In Stock | |
| 500 mg | $1,770 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $171 | In Stock |
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CitedSelect Batch
Purity:98.1%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CHPG hydrochloride is a selective agonist of mGluR5. |
| In vitro | After SO2 derivatives treatment, CHPG hydrochloride (10-500 µM) increases the cell viability and reduces the release of LDH. CHPG hydrochloride (0.5 mM) protects BV2 cells against SO2-induced apoptosis and increases the TSG-6 expression through the TSG-6/NF-κB pathway[1]. |
| In vivo | In adult Sprague-Dawley male rats, injection of CHPG hydrochloride (250 nM) reduces significantly cerebral lesion volume by activation of the ERK and Akt signaling pathways[2]. |
| Alias | CHPG hydrochloride(170846-74-9 Free base) |
| Molecular Weight | 238.07 |
| Formula | C8H9Cl2NO3 |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (126.01 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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