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Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $30 | In Stock | |
50 mg | $43 | In Stock | |
100 mg | $61 | In Stock | |
200 mg | $89 | In Stock | |
500 mg | $148 | In Stock | |
1 mL x 10 mM (in DMSO) | $48 | In Stock |
Description | Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. |
In vivo | Ciclopirox exhibits inhibitory effects on the growth of Candida albicans strain SC5314 (MIC80=1.0-2.0μg/mL) and Aspergillus fumigatus strain B5233 (IC50=4.22 μM). |
Cell Research | Sabouraud glucose medium (2%) is used for cell culture growth, and RPMI 2% glucose medium and 2% Sabouraud glucose medium are used for MIC determinations. For cell culture growth curves, 220 mL of 2% Sabouraud glucose medium containing different concentrations of Ciclopirox are inoculated with 105 cells/mL, and the mixture is shaken at 160 rpm and 37 °C for 1-10 hours. Growth is measured photometrically at 630 nm. FeCl3 or 2,2'-bipyridine is added to the medium at different concentrations for inhibition studie(Only for Reference) |
Alias | Ciclopirox ethanolamine |
Molecular Weight | 268.35 |
Formula | C14H24N2O3 |
Cas No. | 41621-49-2 |
Smiles | NCCO.Cc1cc(=O)n(O)c(c1)C1CCCCC1 |
Relative Density. | 410 g/L. Temperature:25 °C. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 28 mg/mL (104.3 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 3.33 mg/mL (12.42 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
Ethanol
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