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Ciclopirox olamine

🥰Excellent
Catalog No. T1114Cas No. 41621-49-2
Alias Ciclopirox ethanolamine

Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Ciclopirox olamine

Ciclopirox olamine

🥰Excellent
Purity: 100%
Catalog No. T1114Alias Ciclopirox ethanolamineCas No. 41621-49-2
Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$43In Stock
100 mg$61In Stock
200 mg$89In Stock
500 mg$148In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
In vivo
Ciclopirox exhibits inhibitory effects on the growth of Candida albicans strain SC5314 (MIC80=1.0-2.0μg/mL) and Aspergillus fumigatus strain B5233 (IC50=4.22 μM).
Cell Research
Sabouraud glucose medium (2%) is used for cell culture growth, and RPMI 2% glucose medium and 2% Sabouraud glucose medium are used for MIC determinations. For cell culture growth curves, 220 mL of 2% Sabouraud glucose medium containing different concentrations of Ciclopirox are inoculated with 105 cells/mL, and the mixture is shaken at 160 rpm and 37 °C for 1-10 hours. Growth is measured photometrically at 630 nm. FeCl3 or 2,2'-bipyridine is added to the medium at different concentrations for inhibition studie(Only for Reference)
AliasCiclopirox ethanolamine
Chemical Properties
Molecular Weight268.35
FormulaC14H24N2O3
Cas No.41621-49-2
SmilesNCCO.Cc1cc(=O)n(O)c(c1)C1CCCCC1
Relative Density.410 g/L. Temperature:25 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 28 mg/mL (104.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 3.33 mg/mL (12.42 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM3.7265 mL18.6324 mL37.2648 mL186.3238 mL
5 mM0.7453 mL3.7265 mL7.4530 mL37.2648 mL
10 mM0.3726 mL1.8632 mL3.7265 mL18.6324 mL
Ethanol
1mg5mg10mg50mg
20 mM0.1863 mL0.9316 mL1.8632 mL9.3162 mL
50 mM0.0745 mL0.3726 mL0.7453 mL3.7265 mL
100 mM0.0373 mL0.1863 mL0.3726 mL1.8632 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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