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Delpazolid

Delpazolid
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Purity:99.87%
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Delpazolid

Catalog No. T4165Cas No. 1219707-39-7
Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
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Pack SizePriceAvailabilityQuantity
1 mg$39In Stock
5 mg$73In Stock
10 mg$113In Stock
25 mg$228In Stock
50 mg$347In Stock
100 mg$488In Stock
500 mg$1,060In Stock
1 mL x 10 mM (in DMSO)$80In Stock
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Product Introduction

Bioactivity
Description
Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
AliasLCB01-0371
Chemical Properties
Molecular Weight308.31
FormulaC14H17FN4O3
Cas No.1219707-39-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 13 mg/mL (42.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2435 mL16.2174 mL32.4349 mL162.1744 mL
5 mM0.6487 mL3.2435 mL6.4870 mL32.4349 mL
10 mM0.3243 mL1.6217 mL3.2435 mL16.2174 mL
20 mM0.1622 mL0.8109 mL1.6217 mL8.1087 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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