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DMAT
DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
Catalog No. T7390Cas No. 749234-11-5
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Purity:99.48%
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DMAT
Catalog No. T7390Alias CK2 Inhibitor, Casein kinase II InhibitorCas No. 749234-11-5
DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $34 | In Stock | |
| 10 mg | $48 | In Stock | |
| 25 mg | $93 | In Stock | |
| 50 mg | $169 | In Stock | |
| 100 mg | $219 | In Stock | |
| 200 mg | $326 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $54 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM). |
| Targets&IC50 | CK2:0.13 μM (IC50, Human CK2) , DYRK2:0.35 μM , HIPK3:0.59 μM , DYRK1A:0.41 μM , HIPK2:0.37 μM , Pim3:0.097 μM , PKD1:0.18 μM , Pim1:0.148 μM , CDK2:0.64 μM, Pim2:1.6 μM , β-glucuronidase:1.7 μM |
| In vivo | DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts[1][2]. |
| Alias | CK2 Inhibitor, Casein kinase II Inhibitor |
| Molecular Weight | 476.79 |
| Formula | C9H7Br4N3 |
| Cas No. | 749234-11-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (104.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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