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DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $56 | In Stock | |
10 mg | $81 | In Stock | |
25 mg | $155 | In Stock | |
50 mg | $281 | In Stock | |
100 mg | $365 | In Stock | |
1 mL x 10 mM (in DMSO) | $90 | In Stock |
Description | DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM). |
Targets&IC50 | CK2:0.13 μM (IC50, Human CK2) , DYRK2:0.35 μM , HIPK3:0.59 μM , DYRK1A:0.41 μM , HIPK2:0.37 μM , PKD1:0.18 μM , Pim1:0.148 μM , Pim3:0.097 μM , Pim2:1.6 μM , CDK2:0.64 μM, β-glucuronidase:1.7 μM |
In vivo | DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts[1][2]. |
Alias | CK2 Inhibitor, Casein kinase II Inhibitor |
Molecular Weight | 476.79 |
Formula | C9H7Br4N3 |
Cas No. | 749234-11-5 |
Smiles | CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 |
Relative Density. | 2.410 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (104.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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