Shopping Cart
- Remove All
Your shopping cart is currently empty
Donitriptan
😃Good
Catalog No. T11075Cas No. 170912-52-4
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively.
Donitriptan
😃Good
Purity: 98.34%
Catalog No. T11075Cas No. 170912-52-4
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $51 | In Stock | |
| 2 mg | $74 | In Stock | |
| 5 mg | $122 | 6-8 weeks | |
| 10 mg | $198 | 6-8 weeks | |
| 25 mg | $455 | 6-8 weeks | |
| 50 mg | $672 | 6-8 weeks | |
| 1 mL x 10 mM (in DMSO) | $133 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Donitriptan"
Alverine citrate
NSC 35459
T04285560-59-8
Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.
- $41
Size
QTY
Dapoxetine hydrochloride
LY-210448 hydrochloride, Dapoxetine HCl
T6461129938-20-1
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
- $30
Size
QTY
Trazodone hydrochloride
Trazodone HCl, KB-831, AF-1161
T161925332-39-2
Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety.
- $39
Size
QTY
Clozapine N-Oxide
Cited
T449434233-69-7
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.
- $30
Size
QTY
CitedMianserin hydrochloride
ORG GB-94 HCl, Mianserin HCl
T078321535-47-7
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant properties that blocks alpha-adrenergic, histamine H1, and certain serotonin receptors; it may cause drowsiness and hematological issues.
- $30
Size
QTY
Cinchonidine
α-Quinidine, L-Cinchonidine
T1317485-71-2
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
- $31
Size
QTY
Amitriptyline hydrochloride
Tryptizol, Domical, Annoyltin, Amitriptyline HCl
T0678549-18-8
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
5-HT ReceptorAChRAdrenergic ReceptorHistamine ReceptorNorepinephrineSerotonin TransporterSigma receptorSodium ChannelTrk receptor
- $45
Size
QTY
Fluoxetine hydrochloride Cited
LY-110140, Lilly110140, Fluoxetine HCl
T0450L56296-78-7
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
- $48
Size
QTY
CitedCloperastine hydrochloride
HT-11 hydrochloride
T072314984-68-0
Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.
- $31
Size
QTY
Olanzapine Cited
LY170053
T1567132539-06-1
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
- $30
Size
QTY
CitedMirtazapine
Org3770, 6-Azamianserin
T013785650-52-8
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.
- $34
Size
QTY
Serotonin hydrochloride Cited
Serotonin HCl, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride, 5-HT HCl
T2209153-98-0
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
- $30
Size
QTY
CitedSelect Batch
Purity:98.34%
Contact us for more batch information
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.Product Introduction
Bioactivity
Chemical Properties
| Description | Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively. |
| Targets&IC50 | 5-HT1D receptor:9.3 (pki), 5-HT1B receptor:9.4 (pki), pki: |
| Molecular Weight | 403.48 |
| Formula | C23H25N5O2 |
| Cas No. | 170912-52-4 |
| Smiles | NCCc1c[nH]c2ccc(OCC(=O)N3CCN(CC3)c3ccc(cc3)C#N)cc12 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 245 mg/mL (607.22 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Donitriptan | purchase Donitriptan | Donitriptan cost | order Donitriptan | Donitriptan chemical structure | Donitriptan formula | Donitriptan molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.