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Doxapram hydrochloride hydrate

Doxapram hydrochloride hydrate
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Purity:100%
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Doxapram hydrochloride hydrate

Catalog No. T0038Cas No. 7081-53-0
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 values of 410 nM, 37 μM, and 9 μM, respectively.
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Pack SizePriceAvailabilityQuantity
10 mg$34In Stock
25 mg$51In Stock
50 mg$68In Stock
100 mg$117In Stock
200 mg$182In Stock
1 mL x 10 mM (in DMSO)$76In Stock
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Product Introduction

Bioactivity
Description
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 values of 410 nM, 37 μM, and 9 μM, respectively.
AliasDoxapram hydrochloride monohydrate, Doxapram HCl
Chemical Properties
Molecular Weight432.99
FormulaC24H33ClN2O3(C24H30N2O2·ClH·H2O)
Cas No.7081-53-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 81 mg/mL (187.1 mM)
Ethanol: 2 mg/mL (4.61 mM)
H2O: 23 mg/mL (53.1 mM)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.3095 mL11.5476 mL23.0952 mL115.4761 mL
DMSO
1mg5mg10mg50mg
5 mM0.4619 mL2.3095 mL4.6190 mL23.0952 mL
10 mM0.2310 mL1.1548 mL2.3095 mL11.5476 mL
20 mM0.1155 mL0.5774 mL1.1548 mL5.7738 mL
50 mM0.0462 mL0.2310 mL0.4619 mL2.3095 mL
100 mM0.0231 mL0.1155 mL0.2310 mL1.1548 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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