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EAD1 TFA(1644388-26-0 Free base)

Catalog No. T35329L CAS 2320427-95-8

Synonyms: EAD1 HCL(1644388-26-0 Free base)

EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis

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EAD1 TFA(1644388-26-0 Free base) Chemical Structure

EAD1 TFA(1644388-26-0 Free base), CAS 2320427-95-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 97.00
2 mg	In stock	$ 143.00
5 mg	In stock	$ 263.00
10 mg	In stock	$ 389.00
25 mg	In stock	$ 638.00
50 mg	In stock	$ 882.00
1 mL * 10 mM (in DMSO)	In stock	$ 325.00

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Purity: 97.49%

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Description	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis
Targets&IC50	Autophagy (BxPC3 cells):5.8 μM
In vitro	EAD1 HCL (0-200 μM; 72 hours) has antiproliferative activity against human cancer cell lines. EAD1 HCL (5-75 μM; 24 hours) induces apoptosis in the H460 cells in a concentration-dependent manner. EAD1 HCL (1-25 μM; 24 hour) increases the punctate LC3 signal in H460 cells[1].

Synonyms	EAD1 HCL(1644388-26-0 Free base)
Molecular Weight	598.45
Formula	C26H28Cl2F3N7O2
CAS No.	2320427-95-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (105.59 mM)

References and Literature

1. Lars Ulrik Nordstrøm, et al. ACS Med Chem Lett. 2015, 6(2): 134-139.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library

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Keywords

EAD1 TFA(1644388-26-0 Free base) 2320427-95-8 Apoptosis Autophagy EAD1 HCL(1644388-26-0 Free base) inhibitor inhibit

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