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Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $39 | In Stock | |
50 mg | $58 | In Stock | |
100 mg | $86 | In Stock | |
200 mg | $125 | In Stock | |
500 mg | $215 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis. |
Kinase Assay | The inhibition profile of Cabozantinib against a broad panel of 270 human kinases is determined using luciferase-coupled chemiluminescence, 33P-phosphoryl transfer, or AlphaScreen technology. Recombinant human full-length, glutathione S-transferase tag, or histidine tag fusion proteins are used, and IC50 values are determined by measuring phosphorylation of peptide substrate poly(Glu, Tyr) at ATP concentrations at or below the Km for each respective kinase. The mechanism of kinase inhibition is evaluated using the AlphaScreen Assay by determining the IC50 values over a range of ATP concentrations[2]. |
Alias | TA-2711E, TA-2711 |
Molecular Weight | 402.48 |
Formula | C20H27NaO5S |
Cas No. | 86408-72-2 |
Smiles | [Na+].COC(=O)[C@@H]1CCC[C@@]2(C)[C@@H]1CCc1cc(C(C)C)c(cc21)S([O-])(=O)=O |
Relative Density. | 1.241 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (124.23 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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