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Fialuridine

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Catalog No. T7655Cas No. 69123-98-4
Alias FIAU, DRG-0098

Fialuridine (DRG-0098) is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.

Fialuridine

Fialuridine

🥰Excellent
Purity: 99.90%
Catalog No. T7655Alias FIAU, DRG-0098Cas No. 69123-98-4
Fialuridine (DRG-0098) is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
Pack SizePriceAvailabilityQuantity
1 mg28 €In Stock
5 mg64 €In Stock
10 mg112 €In Stock
25 mg234 €In Stock
50 mg372 €In Stock
100 mg562 €In Stock
500 mg1.216 €In Stock
1 mL x 10 mM (in DMSO)71 €In Stock
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Purity:99.90%
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Product Introduction

Bioactivity
Description
Fialuridine (DRG-0098) is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
In vitro
Fialuridine (FIAU) blocks DNA synthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex[1]
AliasFIAU, DRG-0098
Chemical Properties
Molecular Weight372.09
FormulaC9H10FIN2O5
Cas No.69123-98-4
SmilesOC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)n1cc(I)c(=O)[nH]c1=O
Relative Density.2.18 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (26.88 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6875 mL13.4376 mL26.8752 mL134.3761 mL
5 mM0.5375 mL2.6875 mL5.3750 mL26.8752 mL
10 mM0.2688 mL1.3438 mL2.6875 mL13.4376 mL
20 mM0.1344 mL0.6719 mL1.3438 mL6.7188 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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