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Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | 37 € | In Stock | |
10 mg | 52 € | In Stock | |
25 mg | 77 € | In Stock | |
50 mg | 92 € | In Stock | |
100 mg | 147 € | In Stock | |
500 mg | 367 € | In Stock |
Description | Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker |
In vivo | Fosphenytoin has anticonvulsant activity in a mouse model of maximal electroshock seizures similar to that of phenytoin (ED50s = 16 and 8 mg/kg, respectively). It also has antiarrhythmic activity in isolated guinea pig atria and in anesthetized dogs. Formulations containing fosphenytoin have been used in the treatment of status epilepticus |
Alias | Fosphenytoin sodium, ACC-9653 |
Molecular Weight | 406.24 |
Formula | C16H13N2Na2O6P |
Cas No. | 92134-98-0 |
Smiles | O.[Na+].[Na+].[O-]P([O-])(=O)OCN1C(=O)NC(C1=O)(c1ccccc1)c1ccccc1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 100 mg/mL (246.16 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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